- Author:
- Dewan Sarwar <dsar941@UoA.auckland.ac.nz>
- Date:
- 2020-03-03 10:58:07+13:00
- Desc:
- replaceing https with http
- Permanent Source URI:
- https://models.cellml.org/workspace/267/rawfile/9953bea1fc565b19e663410462fd9529da78a91f/GI Model/NHE3.cellml
<?xml version="1.0" encoding="UTF-8"?>
<model xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cmeta="http://www.cellml.org/metadata/1.0#" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bqs="http://www.cellml.org/bqs/1.0#" xmlns:semsim="http://www.bhi.washington.edu/SemSim#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" name="NHE3" cmeta:id="NHE3">
<units name="flux">
<unit exponent="-3.0" prefix="centi" units="metre" />
<unit prefix="milli" units="mole" />
<unit exponent="-1.0" units="second" />
</units>
<units name="per_millisec">
<unit exponent="-1.0" prefix="milli" units="second" />
</units>
<units name="millisec">
<unit prefix="milli" units="second" />
</units>
<units name="mM">
<unit prefix="milli" units="mole" />
<unit exponent="-1.0" units="litre" />
</units>
<component name="environment">
<variable cmeta:id="environment.time" name="time" public_interface="out" units="second" />
</component>
<component name="NHE3">
<variable cmeta:id="NHE3.C_lumen_Na" name="C_lumen_Na" public_interface="in" units="mM" />
<variable cmeta:id="NHE3.C_int_Na" name="C_int_Na" public_interface="in" units="mM" />
<variable cmeta:id="NHE3.C_lumen_H" name="C_lumen_H" public_interface="in" units="mM" />
<variable cmeta:id="NHE3.C_int_H" name="C_int_H" public_interface="in" units="mM" />
<variable cmeta:id="NHE3.J_Na" name="J_Na" public_interface="in" units="flux" />
<variable cmeta:id="NHE3.J_H" name="J_H" public_interface="in" units="flux" />
</component>
<rdf:RDF xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:ro="http://www.obofoundry.org/ro/ro.owl#" xmlns:opb="http://bhi.washington.edu/OPB#">
<rdf:Description rdf:about="#NHE3">
<ro:modelOf rdf:resource="http://purl.obolibrary.org/obo/PR_P26433" />
<ro:compartmentOf rdf:resource="http://purl.obolibrary.org/obo/FMA_74550" />
<ro:located_in rdf:resource="http://purl.obolibrary.org/obo/FMA_84666" />
<ro:located_in rdf:resource="http://purl.obolibrary.org/obo/FMA_17693" />
<ro:located_in rdf:resource="http://purl.obolibrary.org/obo/FMA_70973" />
<ro:compartmentOf rdf:resource="http://purl.obolibrary.org/obo/FMA_84666" />
<ro:compartmentOf rdf:resource="http://purl.obolibrary.org/obo/FMA_66836" />
</rdf:Description>
<rdf:Description rdf:about="#NHE3.C_int_Na">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_1">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_2">
<ro:part_of>
<rdf:Description rdf:about="#entity_3">
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_66836" />
</rdf:Description>
</ro:part_of>
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29101" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00340" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>concentration of sodium in the cytosol compartment</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#NHE3.J_H">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_5">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#process_1" dcterms:description="">
<semsim:hasMediatorParticipant>
<rdf:Description rdf:about="#mediator_3">
<semsim:hasPhysicalEntityReference>
<rdf:Description rdf:about="#entity_7">
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/PR_P26433" />
</rdf:Description>
</semsim:hasPhysicalEntityReference>
</rdf:Description>
</semsim:hasMediatorParticipant>
<semsim:hasMediatorParticipant>
<rdf:Description rdf:about="#mediator_2">
<semsim:hasPhysicalEntityReference>
<rdf:Description rdf:about="#entity_6">
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_84666" />
</rdf:Description>
</semsim:hasPhysicalEntityReference>
</rdf:Description>
</semsim:hasMediatorParticipant>
<semsim:hasSinkParticipant>
<rdf:Description rdf:about="#sink_1" semsim:hasMultiplier="1.0">
<semsim:hasPhysicalEntityReference>
<rdf:Description rdf:about="#entity_4">
<ro:part_of>
<rdf:Description rdf:about="#entity_1">
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/FMA_74550" />
</rdf:Description>
</ro:part_of>
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/CHEBI_15378" />
</rdf:Description>
</semsim:hasPhysicalEntityReference>
</rdf:Description>
</semsim:hasSinkParticipant>
<semsim:hasSourceParticipant>
<rdf:Description rdf:about="#source_1" semsim:hasMultiplier="1.0">
<semsim:hasPhysicalEntityReference>
<rdf:Description rdf:about="#entity_5">
<ro:part_of rdf:resource="#entity_3" />
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/CHEBI_15378" />
</rdf:Description>
</semsim:hasPhysicalEntityReference>
</rdf:Description>
</semsim:hasSourceParticipant>
<semsim:name>H flow from cytosol to luminal</semsim:name>
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00593" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Flux of hydrogen from cytosol to luminal through NHE3 and apical membrane</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#NHE3.C_lumen_Na">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_0">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#entity_0">
<ro:part_of rdf:resource="#entity_1" />
<semsim:hasPhysicalDefinition rdf:resource="http://purl.obolibrary.org/obo/CHEBI_29101" />
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00340" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>concentration of sodium in the luminal compartment</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#NHE3" semsim:modelId="NHE3" semsim:modelName="NHE3" />
<rdf:Description rdf:about="#NHE3.J_Na">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_4">
<semsim:physicalPropertyOf>
<rdf:Description rdf:about="#process_0" dcterms:description="">
<semsim:hasMediatorParticipant>
<rdf:Description rdf:about="#mediator_1">
<semsim:hasPhysicalEntityReference rdf:resource="#entity_7" />
</rdf:Description>
</semsim:hasMediatorParticipant>
<semsim:hasMediatorParticipant>
<rdf:Description rdf:about="#mediator_0">
<semsim:hasPhysicalEntityReference rdf:resource="#entity_6" />
</rdf:Description>
</semsim:hasMediatorParticipant>
<semsim:hasSinkParticipant>
<rdf:Description rdf:about="#sink_0" semsim:hasMultiplier="1.0">
<semsim:hasPhysicalEntityReference rdf:resource="#entity_2" />
</rdf:Description>
</semsim:hasSinkParticipant>
<semsim:hasSourceParticipant>
<rdf:Description rdf:about="#source_0" semsim:hasMultiplier="1.0">
<semsim:hasPhysicalEntityReference rdf:resource="#entity_0" />
</rdf:Description>
</semsim:hasSourceParticipant>
<semsim:name>Na flow from luminal to cytosol</semsim:name>
</rdf:Description>
</semsim:physicalPropertyOf>
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00593" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>Flux of sodium from luminal to cytosol through NHE3 and apical membrane</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#NHE3.C_int_H">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_3">
<semsim:physicalPropertyOf rdf:resource="#entity_5" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00340" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>concentration of hydrogen in the cytosol compartment</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#NHE3.C_lumen_H">
<semsim:isComputationalComponentFor>
<rdf:Description rdf:about="#property_2">
<semsim:physicalPropertyOf rdf:resource="#entity_4" />
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_00340" />
</rdf:Description>
</semsim:isComputationalComponentFor>
<dcterms:description>concentration of hydrogen in the luminal compartment</dcterms:description>
</rdf:Description>
<rdf:Description rdf:about="#environment.time" dcterms:description="Time">
<semsim:hasPhysicalDefinition rdf:resource="http://identifiers.org/opb/OPB_01023" />
</rdf:Description>
</rdf:RDF>
</model>
